Certified Organic Full Spectrum Reishi Extract
12% Beta Glucan (polysaccharide) 6% Triterpenes (ganoderic acids)

The Reishi mushroom is one of the most revered herbs in Traditional Chinese Medicine (TCM). Now known as Ling zhi in China, there are references to its use in that country as far back as 100 B.C. where it was referred to as the "Herb of Spiritual Potency" and the "Ten-thousand Year Mushroom". The focus of TCM is on actively promoting good health and the prevention of health problems. Reishi is one of the most highly regarded herbs in TCM for this purpose and the mushroom most often used as a general health tonic. Modern clinical research also supports many of the uses for this mushroom as described in TCM. It benefits immune health, cardiovascular health, and liver function.1 Research has also shown Reishi extracts to oxygenate the blood2. Reishi mushroom extracts are frequently used by mountain climbers to combat altitude sickness and are contained in many of the performance enhancing herbal formulas used by Chinese athletes.
Reishi Gano 161™
In development for over four years, Reishi Gano 161™ represents the future of mushroom supplements. Using HPLC analysis of the triterpenes as the criteria for strain selection, various strains of Reishi were crossed (161 times), resulting in a strain with the very highest levels of anti-inflammatory triterpenes. The subject of a series of human clinical studies at a major U.S. University, Reishi Gano 161™ delivers the very best health benefits this ancient mushroom has to offer and is the finest Reishi supplement available in the world. Reishi Gano 161™ is a super strength extract and is not diluted with un-extracted mushroom or mycelium powder like most commercially available Reishi products. It is carefully processed with hot water and alcohol to ensure the presence of all the important bio-active compounds.
Clinical Research
Reishi is one of the most widely researched natural remedies in Asia, with most of the research centering on three actions: hepatic support,* immune modulation,* and cardiovascular-regulation.* MushroomScience is sponsoring research on the Gano 161™ strain, focusing on the anti-inflammatory properties. The first study focused on the mechanism of action and found that the triterpenes in Reishi Gano 161 ™ down-regulate Tumor Necrosis Factor-a and block the activation of NF Kappa-ß when outside the normal range, interrupting the inflammatory cascade at two separate points. This anti-inflammatory effect occurs at the same time the polysaccharides are stimulating the TH1 cellular immune response.3 This could be a potentially useful combination when treating conditions involving both depressed immunity and inflammation.
Traditional Use and Preparation
Reishi is mild and warming in nature, with a bitter taste. In TCM it is used to nourish, tonify, remove toxins and disperse accumulation. It is used as a tonic for symptoms of weakness or debility and as a sedative for dizziness and insomnia due to neurasthenia and hypertension.4 All available references from TCM have Reishi prepared as a hot-water extraction/decoction.5 Active Constituents
Triterpenes (Ganoderic Acids), Polysaccharides (1-3 linked proteoglycans extracted from the cell walls).
Extraction Information
Hot water extracted concentrates from the mushroom (fruiting stage) have been used in 100% of all the published clinical research done on Reishi.6 This also conforms to the uses and preparation methods described in TCM. A hot water extract is, on average, 80 times more potent than mycelium biomass. Also, many of the triterpenes and other important constituents that benefit cardiovascular health* and effect inflammation are found only in the mushroom fruit bodies, not the mycelium.7 Our Reishi Gano 161 fruit-body extract is a carefully processed hot water extraction using both water and alcohol, ensuring the presence of all the important bio-active compounds.